Giving prophylactic antibiotics within 1 hour before cesarean incision instead of after umbilical cord clamping reduced surgical site infections by 48%, according to a 96-month retrospective cohort study.

The study, by Nupur D. Kittur, PhD, MPH, from the Department of Medicine and the Department of Obstetrics and Gynecology at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, Missouri, and colleagues, included of 8668 women who underwent cesarean delivery from January 2003 to December 2010 in a US tertiary-care hospital. The results are published in the August issue of Obstetrics & Gynecology.

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